CLINICAL CORNER

SHORTAGES Update

Bicillin L-A Shortage Update

CPS currently has a limited supply of Bicillin L-A (penicillin G Benzathine) injection in stock.  All products are currently on backorder due to manufacturing delays.   CPS is in close contact with wholesalers regarding this shortage and it is anticipated the manufacture will be shipping product soon.

Bicillin L-A is penicillinase-sensitive penicillin indicated for mild to moderate upper respiratory Streptococcus infections and syphilis.  Bicillin L-A is the recommended treatment for syphilis and is the only option for pregnant women infected with or exposed to syphilis.

The Centers for Disease Control and Prevention (CDC) recommends that until the shortage of Bicillin L-A is resolved, clinicians should consider prioritizing Bicillin L-A for the treatment of syphilis in pregnant women.  Although data to support the use of alternatives to penicillin is limited, options for non-pregnant patients may include doxycycline, tetracycline, and for neurosyphilis, ceftriaxone. These therapies should be used only in conjunction with close clinical and laboratory follow-up to ensure appropriate serological response and cure.

Tylenol (Acetaminophen) ER 650mg shortage is currently resolved

Normal Saline Add-vantage shortage is currently resolved

Pipercillin/Tazobactam (Zosyn) shortage is currently resolved.  Please note that Zosyn is only available in Add-vantage.

  • Zosyn is a combination penicillin antibiotic.
  • Alternatives to treat healthcare-associated pneumonia include Meropenem OR doripenem PLUS either Levofloxacin OR aztreonam OR amikacin.

Cefepime 2 gm and Cefepime 2 gm Add-vantage are on back order.   Currently only 1 gm products are available.  Resolution of this shortage is estimated in July 2016.

  • Cefepime is a 4th generation Cephalosporin.
  • Alternatives to treat healthcare-associated pneumonia include Meropenem OR doripenem PLUS either Levofloxacin OR aztreonam OR amikacin.

Please contact Kimberly Griego, PharmD at KGriego@contractpharmacy.com or 267-487-9033 with any questions.

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